Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17336430 | 0.89 | PPIB (0.52) | PPIBLMNAALDH1A1HTTSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL18614060 | 0.85 | CYP1A2 (0.42) | MLYCDALDH1A1SMN1; SMN2MAPK1 | |
| Trifluoroacetic Acid SCHEMBL29472308 | 0.84 | POLQ (0.48) | MLYCDLMNA | |
| Trifluoroacetic Acid SCHEMBL29472278 | 0.83 | POLQ (0.54) | MLYCDALDH1A1 | |
| SCHEMBL22312030 | 0.81 | POLB (0.43) | MLYCDLMNA | |
| Trifluoroacetic Acid SCHEMBL17336564 | 0.80 | PPIB (0.49) | MLYCDPPIBLMNAALDH1A1HTT | |
| Trifluoroacetic Acid SCHEMBL4705712 | 0.79 | POLQ (0.49) | MLYCDALDH1A1 | |
| Hydrochloric Acid SCHEMBL29472259 | 0.79 | POLB (0.43) | MLYCDLMNA | |
| SCHEMBL9155738 | 0.77 | LMNA (0.46) | PPIBLMNA | |
| SCHEMBL29694171 | 0.77 | HSP90AA1 (0.48) | ALDH1A1HTTSMN1; SMN2HSP90AA1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220098154-A1 | ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098154-A1 | ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | POLQ, POLH, POLB | MLYCD 1156/4885PPIB 3173/4885LMNA 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.