SCHEMBL2947259

SCHEMBL2947259

CC(C)C(C)(C(=O)N(C)C)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28539062 0.79 POLB (0.32) POLB
SCHEMBL5518522 0.78 ALDH1A1 (0.32) ALDH1A1TSHRPOLB
SCHEMBL20402670 0.76 POLB (0.33) POLB
SCHEMBL12927421 0.74
SCHEMBL17967109 0.72 DPP4 (0.36)
SCHEMBL1106444 0.72
SCHEMBL26865121 0.70 ALDH1A1 (0.31) ALDH1A1
SCHEMBL380594 0.70 CYP1A2 (0.32)
SCHEMBL24050929 0.70 CHRM2 (0.33) ALDH1A1TSHR
SCHEMBL16944043 0.69 ALDH1A1 (0.39) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120323198-A1 ARTICLES COMPRISING A MINT ODOR-FREE COOLING AGENT PESCE ANTONELLA (IT) 2012-12-20 US claimed
US-20040081680-A1 Articles comprising a mint odor-free cooling agent THE PROCTER & GAMBLE COMPANY 2004-04-29 US claimed
WO-2002083192-A1 ARTICLES COMPRISING A MINT ODOR-FREE COOLING AGENT THE PROCTER & GAMBLE COMPANY (US) 2002-10-24 WO claimed
EP-1250941-A1 Articles comprising a mint odor-free cooling agent THE PROCTER & GAMBLE COMPANY (US) 2002-10-23 EP claimed
EP-1250914-B2 Cooling compositions PROCTER & GAMBLE (US) 2015-11-25 EP disclosed
US-20120323198-A1 ARTICLES COMPRISING A MINT ODOR-FREE COOLING AGENT PESCE ANTONELLA (IT) 2012-12-20 US disclosed
US-8273367-B2 In particular to hygienic disposable absorbent articles like sanitary napkins, panty liners, tampons, incontinent pads, diapers, interlabial pads, breast pads, perspiration pads THE PROCTER AND GAMBLE COMPANY (US) 2012-09-25 US disclosed
EP-1250940-B1 An absorbent article comprising an agent able to convey a perception to the wearer PROCTER & GAMBLE (US) 2010-01-06 EP disclosed
EP-1250914-B1 Cooling compositions PROCTER & GAMBLE (US) 2006-05-31 EP disclosed
US-6972010-B2 Absorbent article comprising an agent able to convey a perception to the wearer, without the need to create the external condition perceived THE PROCTER & GAMBLE COMPANY (US) 2005-12-06 US disclosed
US-20050203473-A1 Improved comfort/freshness; feminine hygienic disposable sanitary napkins and/or panty liners; ketal , carboxamides, cyclohexanol, camphor etc. as cooling agents chemically stimulate the thermo-receptors of human skin and/or mucosal surface to convey a freshness sensation to the wearer THE PROCTER & GAMBLE COMPANY (US) 2005-09-15 US disclosed
US-20040081680-A1 Articles comprising a mint odor-free cooling agent THE PROCTER & GAMBLE COMPANY 2004-04-29 US disclosed
WO-2002083192-A1 ARTICLES COMPRISING A MINT ODOR-FREE COOLING AGENT THE PROCTER & GAMBLE COMPANY (US) 2002-10-24 WO disclosed
WO-2002083095-A1 COOLING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-10-24 WO disclosed
EP-1250941-A1 Articles comprising a mint odor-free cooling agent THE PROCTER & GAMBLE COMPANY (US) 2002-10-23 EP disclosed
EP-1250914-A1 Cooling compositions THE PROCTER & GAMBLE COMPANY (US) 2002-10-23 EP disclosed
EP-1250940-A1 An absorbent article comprising an agent able to convey a perception to the wearer THE PROCTER & GAMBLE COMPANY (US) 2002-10-23 EP disclosed
US-4296255-A USEFUL IN TOILETRIES WILKINSON SWORD LIMITED (GB) 1981-10-20 US disclosed
US-4230688-A FOODS, TOILETRIES WILKINSON SWORD LIMITED (GB) 1980-10-28 US disclosed
US-4153679-A IN TOILETRIES, FOODS, BEVERAGES AND TOBACCO PRODUCTS WILKINSON SWORD LIMITED (GB) 1979-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040081680-A1 Articles comprising a mint odor-free cooling agent NAPRT, TAAR1, PNN ALDH1A1 380/4885TSHR 1580/4885POLB 3391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.