Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18122030 | 1.00 | ADORA3 (0.57) | ADORA3ADORA1ADORA2AESR2MAPT | |
| SCHEMBL28748648 | 0.86 | ESR2 (0.46) | ADORA3ADORA1ADORA2AESR2MAPT | |
| SCHEMBL14005778 | 0.81 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AESR2MAPT | |
| SCHEMBL28541224 | 0.81 | ADORA1 (0.59) | ADORA3ADORA1ADORA2AESR2MAPT | |
| SCHEMBL29472984 | 0.81 | ADORA1 (0.59) | ADORA3ADORA1ADORA2AESR2MAPT | |
| SCHEMBL29472998 | 0.80 | PARP1 (0.56) | ADORA3ADORA2AESR2MAPTNPC1 | |
| SCHEMBL2627243 | 0.80 | ESR2 (0.47) | ADORA3ADORA1ADORA2AESR2MAPT | |
| SCHEMBL28748736 | 0.80 | ESR2 (0.47) | ADORA3ESR2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL28550590 | 0.80 | PARP1 (0.56) | ADORA3ADORA2AESR2MAPTNPC1 | |
| SCHEMBL29028688 | 0.80 | NPC1 (0.46) | ADORA3ADORA1ADORA2AESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184598-A | Photocatalytic preparation method and application of N- (2-phenyl-2H-indazole-3-yl) benzamide compound | 河南师范大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-115385858-B | Photocatalytic preparation method of 2-phenyl-2H-indazole-3-carboxamide compound | 河南师范大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-113698349-B | Aqueous phase photocatalysis preparation method of 2- (2-phenyl-2H-indazole-3-yl) acetate compound | 河南师范大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-115385858-A | Photocatalytic preparation method of 2-phenyl-2H-indazole-3-formamide compound | 河南师范大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-114989089-A | Photocatalytic preparation method of 3-alkyl-2-phenyl indazole compound | 河南师范大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-112574112-B | Method for synthesizing N-substituted 2H-indazole compound through oxidation | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |