Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 16/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | EZH1 | Q92800 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28609618 | 1.00 | EZH2 (0.42) | EZH2EPHX2EZH1 | |
| SCHEMBL29473821 | 0.98 | EZH2 (0.43) | EZH2EPHX2EZH1 | |
| SCHEMBL28593420 | 0.98 | EZH2 (0.43) | EZH2EPHX2EZH1 | |
| SCHEMBL29473816 | 0.89 | KDM4E (0.45) | EZH2EZH1 | |
| SCHEMBL28594996 | 0.89 | KDM4E (0.45) | EZH2EZH1 | |
| SCHEMBL29473819 | 0.87 | EZH2 (0.43) | EZH2EZH1 | |
| SCHEMBL29473804 | 0.87 | L3MBTL1 (0.48) | EZH2EZH1 | |
| SCHEMBL28600925 | 0.87 | L3MBTL1 (0.48) | EZH2EZH1 | |
| SCHEMBL28598218 | 0.87 | EZH2 (0.43) | EZH2EZH1 | |
| SCHEMBL28597525 | 0.86 | EZH2 (0.42) | EZH2EZH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045494-B | Pyridone derivative and application thereof in preparation of drugs for preventing and/or treating tuberculosis caused by mycobacterium tuberculosis | 四川大学华西医院 | 2022-04-26 | — | — | CN | disclosed |