Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | NTSR2 | O95665 | 7/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 6/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.45 |
| ▸ | APLNR | P35414 | 3/20 | 0.44 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473888 | 0.97 | CAPN1 (0.47) | CAPN1NTSR2NTSR1SORT1APLNR | |
| SCHEMBL29473879 | 0.92 | CAPN1 (0.51) | CAPN1NTSR2NTSR1SORT1MMP1 | |
| SCHEMBL20769313 | 0.87 | ACE (0.58) | NTSR2NTSR1SORT1ACEOPRM1 | |
| SCHEMBL20769315 | 0.87 | ACE (0.58) | NTSR2NTSR1SORT1ACEOPRM1 | |
| SCHEMBL20769314 | 0.87 | ACE (0.58) | NTSR2NTSR1SORT1ACEOPRM1 | |
| SCHEMBL31512206 | 0.87 | ACE (0.58) | NTSR2NTSR1SORT1MMP1MMP3 | |
| SCHEMBL30877897 | 0.86 | ACE (0.51) | CAPN1NTSR2NTSR1SORT1APLNR | |
| SCHEMBL29511965 | 0.85 | APLNR (0.49) | APLNR | |
| SCHEMBL31670630 | 0.85 | NAA50 (0.51) | NTSR2NTSR1APLNROPRM1 | |
| SCHEMBL10646770 | 0.84 | KMT2A (0.53) | CAPN1NTSR2NTSR1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368703-A1 | HMGB1 PROTEIN DERIVATIVES FOR THE REMOVAL OF BIOFILMS | RES INST NATIONWIDE CHILDRENS HOSPITAL (US) | 2025-12-04 | — | — | US | disclosed |
| EP-3565834-B1 | ANTIBODY FRAGMENTS FOR THE TREATMENT OF BIOFILM-RELATED DISORDERS | THE RES INSTITUTE AT NATIONWIDE CHILDRENS HOSPITAL (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4615483-A2 | COMPOSITIONS AND METHODS FOR TREATING BIOFILMS AND NEUTROPHIL EXTRACELLULAR TRAP FORMATION | Research Institute at Nationwide Children's Hospital (US) | 2025-09-17 | — | — | EP | disclosed |
| US-12365710-B2 | HMGB1 protein derivatives for the removal of biofilms | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) | 2025-07-22 | — | — | US | disclosed |
| EP-3328429-B1 | PEPTIDES AND ANTIBODIES FOR THE REMOVAL OF BIOFILMS | THE RES INSTITUTE AT NATIONWIDE CHILDRENS HOSPITAL (US) | 2025-07-16 | — | — | EP | disclosed |
| US-20250188156-A1 | ANTIBODY COMPOSITIONS FOR DISRUPTING BIOFILMS | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | 2025-06-12 | — | — | US | disclosed |
| US-20250116034-A1 | NOVEL METHODS FOR RAPID DETECTION OF IMMUNOGENIC EPITOPES IN BIOTHREAT AGENTS AND EMERGING PATHOGENS FOR PEPTIDE VACCINES AND THERAPEUTICS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2025-04-10 | — | — | US | disclosed |
| CN-119569846-A | HMGB1 protein derivatives for removal of biofilm | 国家儿童医院研究所 | 2025-03-07 | — | — | CN | disclosed |
| US-12239763-B2 | Peptides and antibodies for the removal of biofilms | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) | 2025-03-04 | — | — | US | disclosed |
| CN-119504987-A | Antibody compositions for disrupting biological membranes | 国家儿童医院研究所 | 2025-02-25 | — | — | CN | disclosed |
| CN-116096239-A | Combination therapy for the treatment and prevention of biological membranes | 国家儿童医院研究所 | 2023-05-09 | — | — | CN | disclosed |
| US-11629182-B2 | Compositions and methods for the removal of biofilms | RESEARCH INSTITUTE OF NATIONWIDE CHILDREN'S HOSPITAL (US) | 2023-04-18 | — | — | US | disclosed |
| US-20220275064-A1 | ANTIBODY COMPOSITIONS FOR DISRUPTING BIOFILMS | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | 2022-09-01 | — | — | US | disclosed |
| US-20220238183-A1 | NOVEL METHODS FOR RAPID DETECTION OF IMMUNOGENIC EPITOPES IN BIOTHREAT AGENTS AND EMERGING PATHOGENS FOR PEPTIDE VACCINES AND THERAPEUTICS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | 2022-07-28 | — | — | US | disclosed |
| US-20220204594-A1 | COMPOSITIONS AND METHODS FOR THE REMOVAL OF BIOFILMS | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | 2022-06-30 | — | — | US | disclosed |
| EP-3997120-A2 | ANTIBODY COMPOSITIONS FOR DISRUPTING BIOFILMS | Research Institute at Nationwide Children's Hospital (US) | 2022-05-18 | — | — | EP | disclosed |
| WO-2022094433-A2 | COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) | 2022-05-05 | — | — | WO | disclosed |
| CN-114401986-A | Antibody composition for disrupting biological membranes | 国家儿童医院研究所 | 2022-04-26 | — | — | CN | disclosed |
| EP-3365027-B1 | HU SPECIFIC ANTIBODIES AND THEIR USE IN INHIBITING BIOFILM | RES INST NATIONWIDE CHILDRENS HOSPITAL (US) | 2022-03-30 | — | — | EP | disclosed |
| US-11274144-B2 | Compositions and methods for the removal of biofilms | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) | 2022-03-15 | — | — | US | disclosed |