SCHEMBL29475619

SCHEMBL29475619

O=C(CC12CC3CC(CC(C3)C1)C2)Nc1cccc2nc(NCCNCCO)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 18/20 1.00
P2RX3 P56373 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12891317 1.00 P2RX7 (1.00) P2RX7P2RX3
Hydrochloric Acid SCHEMBL4507870 0.99 P2RX7 (1.00) P2RX7P2RX3
Hydrochloric Acid SCHEMBL31722657 0.99 P2RX7 (1.00) P2RX7P2RX3
SCHEMBL4507991 0.94 P2RX7 (0.89) P2RX7P2RX3
SCHEMBL4507297 0.93 P2RX7 (0.86) P2RX7P2RX3
SCHEMBL4498519 0.92 P2RX7 (0.84) P2RX7P2RX3
SCHEMBL4510913 0.91 P2RX7 (0.83) P2RX7P2RX3
SCHEMBL4513258 0.90 P2RX7 (1.00) P2RX7P2RX3
SCHEMBL4510082 0.90 P2RX7 (0.82) P2RX7P2RX3
SCHEMBL4508275 0.90 P2RX7 (0.82) P2RX7P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034213-A1 SYSTEMS AND METHODS FOR TARGETING NAD-BASED PATHWAYS FOR TREATMENT OF CANCER UNIV HONG KONG (CN) 2026-02-05 US claimed
WO-2025229484-A1 PURINERGIC P2 RECEPTOR ANTAGONISTS FOR USE IN THE TREATMENT OF CONGENITAL SIDEROBLASTIC ANEMIAS UNIVERSITÀ DEGLI STUDI DI BARI ALDO MORO (IT) 2025-11-06 WO claimed
EP-4157288-A2 MODULATORS OF PURINERGIC RECEPTORS AND RELATED IMMUNE CHECKPOINT FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROM Institut Gustave-Roussy (FR) 2023-04-05 EP claimed
US-20260034213-A1 SYSTEMS AND METHODS FOR TARGETING NAD-BASED PATHWAYS FOR TREATMENT OF CANCER UNIV HONG KONG (CN) 2026-02-05 US disclosed
US-20250367144-A1 TREATMENT OF HYPERINFLAMMATORY SYNDROME REMICINE IP B V (NL) 2025-12-04 US disclosed
WO-2025229484-A1 PURINERGIC P2 RECEPTOR ANTAGONISTS FOR USE IN THE TREATMENT OF CONGENITAL SIDEROBLASTIC ANEMIAS UNIVERSITÀ DEGLI STUDI DI BARI ALDO MORO (IT) 2025-11-06 WO disclosed
US-12419848-B2 Treatment of hyperinflammatory syndrome Remicine IP B.V. (NL) 2025-09-23 US disclosed
EP-4582147-A2 TREATMENT OF HYPERINFLAMMATORY SYNDROME Remicine IP B.V. (NL) 2025-07-09 EP disclosed
EP-4125843-B1 TREATMENT OF HYPERINFLAMMATORY SYNDROME REMICINE IP B V (NL) 2025-05-21 EP disclosed
US-20250144021-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2025-05-08 US disclosed
US-12226527-B2 Gel formulations for local drug release TECHNICAL UNIVERSITY OF DENMARK (DK) 2025-02-18 US disclosed
CN-116322702-A Immunomodulation of myeloid-derived suppressor cell function for cancer treatment 萨吉治疗公司 2023-06-23 CN disclosed
US-20230128348-A1 TREATMENT OF HYPERINFLAMMATORY SYNDROME Remicine IP B.V. (NL) 2023-04-27 US disclosed
EP-4157288-A2 MODULATORS OF PURINERGIC RECEPTORS AND RELATED IMMUNE CHECKPOINT FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROM Institut Gustave-Roussy (FR) 2023-04-05 EP disclosed
EP-4125843-A1 TREATMENT OF HYPERINFLAMMATORY SYNDROME Nomoreitis B.V. (BE) 2023-02-08 EP disclosed
CN-115605194-A Treatment of excessive inflammatory syndrome 诺莫雷蒂斯私人有限公司(BE) 2023-01-13 CN disclosed
CN-115501172-A Gel formulations for topical drug delivery 丹麦技术大学 2022-12-23 CN disclosed
US-11510910-B2 HSP90 targeted conjugates and particles and formulations thereof TVA (ABC), LLC (US) 2022-11-29 US disclosed
CN-115151271-A Application of glatiramer acetate in preparation of Abeta 42 toxicity inhibitor and scavenger 长沙英奈发药业有限公司 2022-10-04 CN disclosed
WO-2022061812-A1 USE OF GLATIRAMER ACETATE IN PREPARATION OF Aβ42 TOXICITY INHIBITOR AND SCAVENGER 长沙英奈发药业有限公司 2022-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034213-A1 SYSTEMS AND METHODS FOR TARGETING NAD-BASED PATHWAYS FOR TREATMENT OF CANCER NAMPT, NADK, CD274 P2RX7 44/4885P2RX3 33/4885
US-20250144021-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TREH, GALE, SLC2A8 P2RX7 1330/4885P2RX3 1670/4885
US-12226527-B2 Gel formulations for local drug release TREH, GALE, SLC2A8 P2RX7 1330/4885P2RX3 1670/4885
US-11510910-B2 HSP90 targeted conjugates and particles and formulations thereof HSP90AB1, HSP90AA1, HSP90B1 P2RX7 4130/4885P2RX3 4120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.