SCHEMBL294757

SCHEMBL294757

O=Cc1cccc(F)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 13/20 1.00
TLR2 O60603 1/20 0.52
TLR1 Q15399 1/20 0.52
TLR6 Q9Y2C9 1/20 0.52
TRIM24 O15164 1/20 0.48
TRIM33 Q9UPN9 1/20 0.48
ALB P02768 1/20 0.47
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MCL1 Q07820 1/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375374 1.00 ERN1 (1.00) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL8958081 0.98 ERN1 (0.96) ERN1TLR2TLR1TLR6TRIM24
Ethylene SCHEMBL11602187 0.94 ERN1 (0.88) ERN1TLR2TLR1TLR6TRIM24
Ethylenediamine SCHEMBL11775933 0.92 ERN1 (0.85) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL11775930 0.90 ERN1 (0.81) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL4437283 0.84 ERN1 (0.71) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL454110 0.84 ERN1 (0.72) ERN1TDP1
SCHEMBL419950 0.83 ERN1 (0.76) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL8698633 0.80 ERN1 (0.65) ERN1TLR2TLR1TLR6LMNA
SCHEMBL26095419 0.78 ERN1 (0.62) ERN1TLR2TLR1TLR6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 860 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119411112-A Surface treatment method for improving corrosion resistance of steel surface 佛山市义众金属材料有限公司 2025-02-11 CN claimed
CN-114573609-B Single-molecule magnet based on asymmetric binuclear dysprosium complex and preparation method thereof 桂林理工大学 2024-02-06 CN claimed
CN-117402194-A Preparation method of D-galactosamine hydrochloride 安徽普利药业有限公司 2024-01-16 CN claimed
CN-114933764-B Luminous high-performance PVC optical cable material and preparation method thereof 宁波格亿达光缆科技有限公司 2023-07-21 CN claimed
CN-114573433-B Preparation method of symmetrical 2,2' -dihydroxybenzophenone derivative 中国科学院大连化学物理研究所 2023-05-12 CN claimed
CN-114933764-A Luminous high-performance PVC optical cable material and preparation method thereof 宁波格亿达光缆科技有限公司 2022-08-23 CN claimed
CN-113201233-B Photochromic organic pigment and preparation method thereof 宁波中苑颜料有限公司 2022-07-01 CN claimed
CN-114573609-A Monomolecular magnet based on asymmetric binuclear dysprosium complex and preparation method thereof 桂林理工大学 2022-06-03 CN claimed
CN-113201233-A Photochromic organic pigment and preparation method thereof 宁波中苑颜料有限公司 2021-08-03 CN claimed
CN-112707982-A Ultrahigh molecular weight polyethylene catalyst, and preparation method and application thereof 中山大学 2021-04-27 CN claimed
CN-1394685-A Norbornene catalytic system and its preparation method and application CHINESE ACAD INST CHEMISTRY (CN) 2003-02-05 CN claimed
CN-1390867-A Polymeric catalyst system of norbornaene and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2003-01-15 CN claimed
CN-1388140-A Nickel compound catalyst system for polymerization of norbornene and its prepn CHINESE ACAD INST CHEMISTRY (CN) 2003-01-01 CN claimed
CN-1388139-A Norbornene polymerization catalyst system and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2003-01-01 CN claimed
EP-0267944-A4 BINDING ASSAYS INVOLVING FORMATION AND DETECTION OF LIGHT-SCATTERING CRYSTALS 1990-09-12 EP claimed
EP-0267944-A1 BINDING ASSAYS INVOLVING FORMATION AND DETECTION OF LIGHT-SCATTERING CRYSTALS ARTHUR D. LITTLE, INC. (US) 1988-05-25 EP claimed
US-4727024-A Binding assays involving formation and detection of light scattering crystals ARTHUR D. LITTLE, INC. 1988-02-23 US claimed
WO-1987007027-A1 BINDING ASSAYS INVOLVING FORMATION AND DETECTION OF LIGHT-SCATTERING CRYSTALS ARTHUR D. LITTLE, INC. (US) 1987-11-19 WO claimed
US-4124643-A Preparation of 3-fluorosalicylaldehyde UOP INC. (US) 1978-11-07 US claimed
US-3972945-A Process for the selective synthesis of salicylaldehydes THE GARRETT CORPORATION (US) 1976-08-03 US claimed