Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 15/20 | 0.65 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570779 | 0.84 | CA1 (0.44) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL29375374 | 0.80 | ERN1 (1.00) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL294757 | 0.80 | ERN1 (1.00) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL8958081 | 0.79 | ERN1 (0.96) | ERN1TLR2TLR1TLR6CA1 | |
| Thiourea SCHEMBL28009893 | 0.78 | CA1 (0.41) | ERN1TLR2TLR1TLR6CA1 | |
| 1,2-Dichloroethane SCHEMBL27851355 | 0.76 | CA1 (0.39) | ERN1TLR2TLR1TLR6CA1 | |
| Ethylene SCHEMBL11602187 | 0.76 | ERN1 (0.88) | ERN1TLR2TLR1TLR6MCL1 | |
| Ethylenediamine SCHEMBL11775933 | 0.74 | ERN1 (0.85) | ERN1TLR2TLR1TLR6MCL1 | |
| SCHEMBL91201 | 0.73 | ERN1 (0.61) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL11775930 | 0.73 | ERN1 (0.81) | ERN1TLR2TLR1TLR6MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008813-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |