SCHEMBL29375374

SCHEMBL29375374

O=Cc1cccc(F)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 13/20 1.00
TLR2 O60603 1/20 0.52
TLR1 Q15399 1/20 0.52
TLR6 Q9Y2C9 1/20 0.52
TRIM24 O15164 1/20 0.48
TRIM33 Q9UPN9 1/20 0.48
ALB P02768 1/20 0.47
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MCL1 Q07820 1/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL294757 1.00 ERN1 (1.00) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL8958081 0.98 ERN1 (0.96) ERN1TLR2TLR1TLR6TRIM24
Ethylene SCHEMBL11602187 0.94 ERN1 (0.88) ERN1TLR2TLR1TLR6TRIM24
Ethylenediamine SCHEMBL11775933 0.92 ERN1 (0.85) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL11775930 0.90 ERN1 (0.81) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL4437283 0.84 ERN1 (0.71) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL454110 0.84 ERN1 (0.72) ERN1TDP1
SCHEMBL419950 0.83 ERN1 (0.76) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL8698633 0.80 ERN1 (0.65) ERN1TLR2TLR1TLR6LMNA
SCHEMBL26095419 0.78 ERN1 (0.62) ERN1TLR2TLR1TLR6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080106-A Oleanolic acid acylhydrazone derivative and preparation method and application thereof 2026-05-26 CN disclosed
EP-4676927-A1 HETEROCYCLIC COMPOUNDS AS WRN INHIBITORS Synnovation Therapeutics, Inc. (US) 2026-01-14 EP disclosed
US-12502661-B2 Catalysts for synthesizing cyclic carbonates, preparation methods and uses thereof ANHUI CONCH MATERIAL TECHNOLOGY CO., LTD. (CN) 2025-12-23 US disclosed
US-20250352989-A1 CATALYSTS FOR SYNTHESIZING CYCLIC CARBONATES, PREPARATION METHODS AND USES THEREOF ANHUI CONCH MATERIAL TECH CO LTD (CN) 2025-11-20 US disclosed
EP-4539855-A1 BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF Borah, Inc. (US) 2025-04-23 EP disclosed
WO-2024187049-A1 HETEROCYCLIC COMPOUNDS AS WRN INHIBITORS SYNNOVATION THERAPEUTICS, INC. (US) 2024-09-12 WO disclosed
WO-2023244775-A1 BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF Boehringer Ingelheim Animal Health USA Inc. (US) 2023-12-21 WO disclosed
EP-4168408-A1 COMPOUNDS FOR AND METHODS OF TREATING DISEASES Alterity Therapeutics Limited (AU) 2023-04-26 EP disclosed
WO-2022261466-A1 LIPID CRYSTALLINE COMPOSITIONS WITH ENHANCED STABILITY FOR TOPICAL DELIVERY OF ACTIVE AGENT COMBINATIONS ANKH LIFE SCIENCES LIMITED (IE) 2022-12-15 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-114025847-A Compounds and compositions as modulators of TLR signaling 神经孔疗法股份有限公司 2022-02-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250352989-A1 CATALYSTS FOR SYNTHESIZING CYCLIC CARBONATES, PREPARATION METHODS AND USES THEREOF PBRM1, POLL, PPOX ERN1 3491/4885TLR2 665/4885TLR1 301/4885
US-12502661-B2 Catalysts for synthesizing cyclic carbonates, preparation methods and uses thereof PBRM1, POLL, PPOX ERN1 3491/4885TLR2 665/4885TLR1 301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.