SCHEMBL29476484

SCHEMBL29476484

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 4/20 0.50
▸ C5AR1 P21730 1/20 0.50
▸ KISS1R Q969F8 5/20 0.49
▸ CCKBR P32239 4/20 0.48
▸ TUBB4A P04350 1/20 0.48
▸ TUBB P07437 1/20 0.48
▸ TUBA3C P0DPH7 1/20 0.48
▸ TUBA1B P68363 1/20 0.48
▸ TUBA4A P68366 1/20 0.48
▸ TUBB4B P68371 1/20 0.48
▸ TUBB3 Q13509 1/20 0.48
▸ TUBB2A Q13885 1/20 0.48
▸ TUBB8 Q3ZCM7 1/20 0.48
▸ TUBA3E Q6PEY2 1/20 0.48
▸ TUBA1A Q71U36 1/20 0.48
▸ TUBA1C Q9BQE3 1/20 0.48
▸ TUBB6 Q9BUF5 1/20 0.48
▸ TUBB2B Q9BVA1 1/20 0.48
▸ TUBB1 Q9H4B7 1/20 0.48
▸ GHSR Q92847 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29476447 1.00 MC4R (0.50) MC4RC5AR1KISS1RCCKBRTUBB4A
SCHEMBL29517075 0.95 C5AR1 (0.54) MC4RC5AR1TUBB4ATUBBTUBA3C
SCHEMBL30510367 0.95 MC4R (0.52) MC4RC5AR1KISS1RCCKBRCCKAR
SCHEMBL31555133 0.94 MC4R (0.52) MC4RC5AR1KISS1RTUBB4ATUBB
SCHEMBL29419493 0.94 MC4R (0.52) MC4RC5AR1KISS1RTUBB4ATUBB
SCHEMBL29419550 0.94 MC4R (0.52) MC4RC5AR1KISS1RTUBB4ATUBB
SCHEMBL30118069 0.94 C5AR1 (0.52) MC4RC5AR1KISS1RTUBB4ATUBB
SCHEMBL29666221 0.94 C5AR1 (0.52) MC4RC5AR1KISS1RTUBB4ATUBB
SCHEMBL29476562 0.93 MC4R (0.50) MC4RC5AR1KISS1RTUBB4ATUBB
SCHEMBL29476617 0.93 MC4R (0.50) MC4RC5AR1KISS1RTUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 — — US claimed
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS INC (US) 2026-01-01 — — US claimed
CN-120152725-A Methods of treating obesity using MC4R agonists 节奏制药公司 2025-06-13 — — CN claimed
EP-4554607-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST Rhythm Pharmaceuticals, Inc. (US) 2025-05-21 — — EP claimed
WO-2024015880-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS, INC. (US) 2024-01-18 — — WO claimed
US-11793746-B2 Intense skin hydration systems and methods ZAVERI CHANDA (US) 2023-10-24 — — US claimed
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY IPSEN PHARMA SAS (FR) 2022-10-27 — — US claimed
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2022-04-28 — — US claimed
US-20220105024-A1 Intense Skin Hydration Systems and Methods ZAVERI CHANDA (US) 2022-04-07 — — US claimed
EP-3977978-A1 INTENSE SKIN HYDRATION SYSTEMS AND METHODS Zaveri, Chanda (US) 2022-04-06 — — EP claimed
CN-114259417-A Potent skin hydrating system and method C·扎维拉 2022-04-01 — — CN claimed
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 — — US disclosed
EP-4711004-A2 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS Rhythm Pharmaceuticals, Inc. (US) 2026-03-18 — — EP disclosed
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS INC (US) 2026-01-01 — — US disclosed
EP-4618952-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST Rhythm Pharmaceuticals, Inc. (US) 2025-09-24 — — EP disclosed
EP-3988108-A1 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR-ASSOCIATED DISORDERS IN HETEROZYGOUS CARRIERS Rhythm Pharmaceuticals, Inc. (US) 2022-04-27 — — EP disclosed
US-20220105024-A1 Intense Skin Hydration Systems and Methods ZAVERI CHANDA (US) 2022-04-07 — — US disclosed
EP-3977978-A1 INTENSE SKIN HYDRATION SYSTEMS AND METHODS Zaveri, Chanda (US) 2022-04-06 — — EP disclosed
CN-114259417-A Potent skin hydrating system and method C·扎维拉 2022-04-01 — — CN disclosed
WO-2022067086-A1 METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS RHYTHM PHARMACEUTICALS, INC. (US) 2022-03-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST MC4R, NPY4R, MC3R MC4R 1/4885C5AR1 2625/4885KISS1R 75/4885
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS THRB, MC1R, MC5R MC4R 8/4885C5AR1 1092/4885KISS1R 417/4885
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY MC4R, MC1R, MC3R MC4R 1/4885C5AR1 607/4885KISS1R 155/4885
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS MC3R, MC1R, MC5R MC4R 4/4885C5AR1 72/4885KISS1R 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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