SCHEMBL30510367

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	5/20	0.52

▸	C5AR1	P21730	1/20	0.50

▸	CCKBR	P32239	5/20	0.49

▸	KISS1R	Q969F8	2/20	0.49

▸	CCKAR	P32238	1/20	0.49

▸	CTSL	P07711	2/20	0.48

▸	CTSS	P25774	2/20	0.48

▸	CTSK	P43235	2/20	0.48

▸	CTSH	P09668	1/20	0.48

▸	MMP1	P03956	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29476484	0.95	MC4R (0.50)	MC4RC5AR1CCKBRKISS1RCCKAR
SCHEMBL29476447	0.95	MC4R (0.50)	MC4RC5AR1CCKBRKISS1RCCKAR
SCHEMBL29511062	0.94	MC4R (0.51)	MC4RC5AR1KISS1RCTSLCTSS
SCHEMBL30510360	0.92	C5AR1 (0.58)	MC4RC5AR1
SCHEMBL29517075	0.92	C5AR1 (0.54)	MC4RC5AR1
SCHEMBL10419744	0.92	C5AR1 (0.51)	MC4RC5AR1KISS1RCTSLCTSS
SCHEMBL29419493	0.89	MC4R (0.52)	MC4RC5AR1KISS1R
SCHEMBL31555133	0.89	MC4R (0.52)	MC4RC5AR1KISS1R
SCHEMBL5994667	0.89	MC4R (0.56)	MC4RKISS1R
SCHEMBL29419550	0.89	MC4R (0.52)	MC4RC5AR1KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116507353-A	Methods of treating melanocortin-4 receptor pathway-related disorders	节奏制药公司	2023-07-28	—	—	CN	disclosed