⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29478320 | 0.88 | — | — | |
| SCHEMBL27178360 | 0.82 | — | — | |
| SCHEMBL24293717 | 0.79 | — | — | |
| SCHEMBL29478314 | 0.79 | USP30 (0.35) | — | |
| SCHEMBL29478313 | 0.77 | BACE1 (0.37) | — | |
| SCHEMBL24293443 | 0.77 | BACE1 (0.37) | — | |
| SCHEMBL29478318 | 0.77 | METTL3 (0.42) | — | |
| SCHEMBL29478334 | 0.77 | METTL3 (0.35) | — | |
| SCHEMBL24293496 | 0.77 | — | — | |
| SCHEMBL23458923 | 0.75 | NR1H2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074391-A1 | COMPOUNDS INHIBITORS OF METTL3 | STORM THERAPEUTICS LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |