Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 17/20 | 0.42 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24293763 | 0.94 | METTL3 (0.39) | METTL3METTL14PRMT5SRC | |
| SCHEMBL29478334 | 0.93 | METTL3 (0.35) | METTL3METTL14 | |
| SCHEMBL24293971 | 0.88 | METTL3 (0.32) | METTL3 | |
| SCHEMBL29478323 | 0.86 | METTL3 (0.49) | METTL3METTL14PRMT5 | |
| SCHEMBL29478320 | 0.81 | — | — | |
| SCHEMBL29478327 | 0.77 | — | — | |
| SCHEMBL27178360 | 0.76 | — | — | |
| SCHEMBL24293550 | 0.75 | METTL3 (0.48) | METTL3METTL14SRC | |
| SCHEMBL29478342 | 0.75 | METTL3 (0.48) | METTL3METTL14SRC | |
| SCHEMBL29478309 | 0.74 | METTL3 (0.32) | METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074391-A1 | COMPOUNDS INHIBITORS OF METTL3 | STORM THERAPEUTICS LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |