SCHEMBL294784

SCHEMBL294784

O=C(O)Oc1ccc2ccccc2n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.53
CNR2 P34972 1/20 0.49
KDM4E B2RXH2 6/20 0.46
LMNA P02545 2/20 0.46
RAB9A P51151 4/20 0.45
PRNP P04156 3/20 0.45
RXFP1 Q9HBX9 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
NPC1 O15118 2/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
HDAC8 Q9BY41 1/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 3/20 0.43
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
MAPK10 P53779 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminomethylamide SCHEMBL6564121 0.89 MGAM (0.44) MGAMCNR2KDM4ELMNARAB9A
SCHEMBL6942621 0.86 MGAM (0.41) MGAMCNR2KDM4ELMNARAB9A
SCHEMBL7773905 0.84 KMT2A (0.53) MGAMCNR2KDM4ELMNARAB9A
SCHEMBL29403157 0.84 KMT2A (0.53) MGAMCNR2KDM4ELMNARAB9A
SCHEMBL31140011 0.83 MGAM (0.47) MGAMCNR2KDM4ELMNARAB9A
SCHEMBL4266167 0.83 MAPT (0.49) MGAMCNR2KDM4ELMNARAB9A
SCHEMBL2316635 0.83 MGAM (0.47) MGAMCNR2KDM4ELMNARAB9A
SCHEMBL6945665 0.83 MGAM (0.47) MGAMCNR2KDM4ELMNARAB9A
SCHEMBL9033949 0.83 MGAM (0.47) MGAMCNR2KDM4ELMNARAB9A
SCHEMBL2762995 0.82 KMT2A (0.51) MGAMCNR2KDM4ELMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2554539-B1 Method for producing gamma-spirolactams from cyclic unsaturated carboxylic acids UNIVERSITÄT POTSDAM (DE) 2014-12-10 EP claimed
EP-1403339-B1 Black ink for inkjet recording FUJIFILM CORP (JP) 2013-03-06 EP claimed
EP-2554539-A1 Method for producing gamma-spirolactams from cyclic unsaturated carboxylic acids Universität Potsdam (DE) 2013-02-06 EP claimed
EP-2149551-A1 N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors Bayer Schering Pharma AG (DE) 2010-02-03 EP claimed
EP-1363923-B1 RHODIUM AND IRIDIUM COMPLEXES MERCK PATENT GMBH (DE) 2009-04-01 EP claimed
EP-1562964-B1 PALLADIUM AND PLATINUM COMPLEXES MERCK PATENT GMBH (DE) 2006-07-19 EP claimed
EP-1562964-A1 PALLADIUM AND PLATINUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2005-08-17 EP claimed
WO-2004041835-A1 PALLADIUM AND PLATINUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-21 WO claimed
EP-0765871-B1 Substituted Quinoline-2-carboxamides, their preparation and their use as prolyle-4-hydroxylase Inhibitors FIBROGEN INC (US) 2004-03-31 EP claimed
EP-1363923-A1 RHODIUM AND IRIDIUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2003-11-26 EP claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
EP-0611774-B1 Production of amides and peptides without racemization in the presence of catalytic amounts of a N-hydroxy-compound HOFFMANN LA ROCHE (CH) 1999-05-26 EP claimed
EP-0847994-A1 Process for the preparation of mixed anhydrides F. HOFFMANN-LA ROCHE AG (CH) 1998-06-17 EP claimed
EP-0603557-B1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM CO (US) 1997-07-30 EP claimed
EP-0765871-A1 Substituted Quinoline-2-carboxamides, their preparation and their use as prolyle-4-hydroxylase Inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-02 EP claimed
EP-0611774-A1 Production of amides and peptides without racemization in the presence of catalytic amounts of a N-hydroxy-compound F. HOFFMANN-LA ROCHE AG (CH) 1994-08-24 EP claimed
EP-0377357-B1 Process for the condensation of at least one epoxide on at least one cyclic anhyhride in the presence of a titanium-based catalyst INST FRANCAIS DU PETROLE (FR) 1994-03-23 EP claimed
EP-0360163-B1 Aromatic carboxylic-acid derivatives and their use in combating the growth of undesirable plants BASF AG (DE) 1994-01-12 EP claimed
EP-0256181-B1 NOVEL QUINALDINAMIDE DERIVATIVES AND THEIR PREPARATIONS NIPPON CHEMIPHAR CO., LTD. (JP) 1991-01-23 EP claimed
EP-0097551-B1 USE OF VANADIUM, NIOBIUM AND TANTALUM PEROXIDIC COMPLEXES AS REAGENTS AND CATALYSTS IN THE HYDROXYLATION OF AROMATIC HYDROCARBONS Institut Français du Pétrole (FR) 1986-10-15 EP claimed