Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294784 | 0.83 | MGAM (0.53) | MGAMRAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL4266167 | 0.81 | MAPT (0.49) | MGAMRAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL31140011 | 0.81 | MGAM (0.47) | MGAMRAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL6945665 | 0.81 | MGAM (0.47) | MGAMRAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL2316635 | 0.81 | MGAM (0.47) | MGAMRAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL1462676 | 0.81 | MGAM (0.43) | MGAMRAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL20504504 | 0.79 | MGAM (0.44) | MGAMRAB9ASMN1; SMN2CNR2HDAC8 | |
| SCHEMBL11031958 | 0.79 | MGAM (0.44) | MGAMRAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL29403157 | 0.79 | KMT2A (0.53) | MGAMRAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL7773905 | 0.79 | KMT2A (0.53) | MGAMRAB9ASMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |