Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16449635 | 0.87 | KMT2A (0.45) | MGAMCNR2MAPTALDH1A1GAA | |
| SCHEMBL294784 | 0.83 | MGAM (0.53) | MGAMCNR2HDAC8MAPTALDH1A1 | |
| SCHEMBL7773905 | 0.82 | KMT2A (0.53) | MGAMCNR2MAPTKMT2AMEN1 | |
| SCHEMBL29403157 | 0.82 | KMT2A (0.53) | MGAMCNR2MAPTKMT2AMEN1 | |
| SCHEMBL10709882 | 0.82 | ELANE (0.41) | MGAMCNR2HDAC8MAPTALDH1A1 | |
| SCHEMBL8556578 | 0.82 | KMT2A (0.52) | MGAMMAPTALDH1A1GAAKMT2A | |
| SCHEMBL2316635 | 0.81 | MGAM (0.47) | MGAMCNR2HDAC8MAPTALDH1A1 | |
| SCHEMBL9033949 | 0.81 | MGAM (0.47) | MGAMCNR2HDAC8MAPTALDH1A1 | |
| SCHEMBL31140011 | 0.81 | MGAM (0.47) | MGAMCNR2HDAC8MAPTALDH1A1 | |
| SCHEMBL4266167 | 0.81 | MAPT (0.49) | MGAMCNR2HDAC8MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847994-B1 | Process for the preparation of mixed anhydrides | HOFFMANN LA ROCHE (CH) | 2003-04-09 | — | — | EP | claimed |
| EP-0847994-A1 | Process for the preparation of mixed anhydrides | F. HOFFMANN-LA ROCHE AG (CH) | 1998-06-17 | — | — | EP | claimed |
| EP-0847994-B1 | Process for the preparation of mixed anhydrides | HOFFMANN LA ROCHE (CH) | 2003-04-09 | — | — | EP | disclosed |
| EP-0847994-A1 | Process for the preparation of mixed anhydrides | F. HOFFMANN-LA ROCHE AG (CH) | 1998-06-17 | — | — | EP | disclosed |