⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261678 | 0.80 | ALDH1A1 (0.40) | — | |
| SCHEMBL3193203 | 0.76 | — | — | |
| SCHEMBL17368397 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL22024413 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL12854154 | 0.76 | — | — | |
| SCHEMBL4685300 | 0.74 | ALDH1A1 (0.37) | — | |
| SCHEMBL4682376 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL4685296 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL4685982 | 0.71 | — | — | |
| SCHEMBL4685983 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1061965-A | The 1-Aryimidazole pesticides | RHONE POULENC AGROCHIMIE (FR) | 1992-06-17 | — | — | CN | claimed |
| WO-2017101890-A1 | SPIROKETAL DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION | 上海艾力斯医药科技有限公司 | 2017-06-22 | — | — | WO | disclosed |
| US-7763644-B2 | Imidazole derivatives, processes for preparing them and their uses | UCB PHARMA, S.A. (BE) | 2010-07-27 | — | — | US | disclosed |
| EP-2050736-A1 | Imidazole derivatives, processes for preparing them and their uses | UCB Pharma, S.A. (BE) | 2009-04-22 | — | — | EP | disclosed |
| EP-1706376-B1 | IMIDAZOLE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA SA (BE) | 2009-03-04 | — | — | EP | disclosed |
| US-20080081832-A1 | Imidazole derivatives, processes for preparing them and their uses | UCB, S.A. | 2008-04-03 | — | — | US | disclosed |
| US-7244747-B2 | Imidazole derivatives, processes for preparing them and their uses | UCB, S.A. (BE) | 2007-07-17 | — | — | US | disclosed |
| CN-1857200-A | Medicinel liquid containing proton pump inhibitor | ZHOU HUAYING (CN) | 2006-11-08 | — | — | CN | disclosed |
| EP-1706376-A1 | IMIDAZOLE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2006-10-04 | — | — | EP | disclosed |
| US-20050137241-A1 | Imidazole derivatives, processes for preparing them and their uses | UCB PHARMA, S.A. (BE) | 2005-06-23 | — | — | US | disclosed |
| WO-2005054188-A1 | IMIDAZOLE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2005-06-16 | — | — | WO | disclosed |
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |