Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 19/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 17/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21357595 | 1.00 | F11 (0.49) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL29227916 | 0.90 | F11 (0.48) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30995017 | 0.90 | F11 (0.48) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30995015 | 0.90 | F11 (0.48) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL29479366 | 0.86 | F11 (0.48) | F11KLKB1CYP3A4 | |
| SCHEMBL21357425 | 0.86 | F11 (0.48) | F11KLKB1CYP3A4 | |
| SCHEMBL30623106 | 0.84 | F11 (0.48) | F11KLKB1CYP3A4F2F10 | |
| SCHEMBL30656519 | 0.84 | F11 (0.39) | F11KLKB1CYP3A4NR1I2 | |
| SCHEMBL29089482 | 0.84 | F11 (0.39) | F11KLKB1CYP3A4NR1I2 | |
| SCHEMBL24633281 | 0.83 | F11 (0.50) | F11KLKB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111770917-B | Process for the preparation of two compounds | 拜耳股份公司 | 2023-09-26 | — | — | CN | claimed |
| EP-3765452-B1 | PREPARATIVE PROCESS OF TWO 4-{[(2S)-2-{4-[5-CHLORO-2-(1H-1,2,3-TRIAZOL-1-YL)PHENYL]-5-METHOXY-2-OXOPYRIDIN-1(2H)-YL}BUTANOYL]AMINO}-2-FLUOROBENZAMIDE DERIVATIVES | BAYER AG (DE) | 2022-04-13 | — | — | EP | claimed |
| CN-118406037-B | Triazole derivative and preparation method and application thereof | 四川师范大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-116283750-B | Heterocyclic amide derivative and preparation method and application thereof | 成都泰和伟业生物科技有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-118406037-A | Triazole derivative and preparation method and application thereof | 四川师范大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-116903585-A | Oxo-pyridine derivative and application thereof in medicine | 天津药物研究院有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-111770917-B | Process for the preparation of two compounds | 拜耳股份公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-116283750-A | Heterocyclic amide derivative and preparation method and application thereof | 成都泰和伟业生物科技有限公司 | 2023-06-23 | — | — | CN | disclosed |