Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28706312 | 1.00 | HDAC6 (0.41) | HDAC6SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL28707228 | 0.83 | ACVR1 (0.39) | HDAC6SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL28711103 | 0.81 | CETP (0.41) | HDAC6SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL29479635 | 0.81 | CETP (0.41) | HDAC6SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL29479777 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL28711116 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL23033684 | 0.77 | HPSE (0.42) | HDAC6SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL29479679 | 0.77 | HPSE (0.42) | HDAC6SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL23012902 | 0.76 | PIK3CA (0.63) | HDAC6RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL29479649 | 0.76 | PIK3CA (0.63) | HDAC6RAB9AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |