Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 13/20 | 0.50 |
| ▸ | MAPT | P10636 | 13/20 | 0.50 |
| ▸ | NPC1 | O15118 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | HPGD | P15428 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033343 | 1.00 | RAB9A (0.50) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL29479768 | 0.87 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL28698118 | 0.87 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL29479778 | 0.83 | RAB9A (0.54) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL28711039 | 0.83 | RAB9A (0.54) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL28710776 | 0.82 | RAB9A (0.38) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL28710798 | 0.81 | NPC1 (0.41) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL29479707 | 0.81 | NPC1 (0.41) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL23012894 | 0.81 | RAB9A (0.39) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL23033302 | 0.80 | CETP (0.48) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |