Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | UTRN | P46939 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28710798 | 1.00 | NPC1 (0.41) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL28714608 | 0.87 | GPR119 (0.42) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL29479720 | 0.87 | GPR119 (0.42) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL23012113 | 0.84 | MMP2 (0.51) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL29479678 | 0.84 | MMP2 (0.51) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL23012350 | 0.82 | MAPT (0.47) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL23033343 | 0.81 | RAB9A (0.50) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL29479768 | 0.81 | SMN1; SMN2 (0.49) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL29479680 | 0.81 | RAB9A (0.50) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL28698118 | 0.81 | SMN1; SMN2 (0.49) | NPC1RAB9AMAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |