Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23034194 | 1.00 | KMO (0.40) | KMOHDAC6ALDH1A1NPC1RAB9A | |
| SCHEMBL28707215 | 0.86 | MAPT (0.40) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29479806 | 0.86 | MAPT (0.40) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29479728 | 0.85 | KMO (0.41) | KMOHDAC6ALDH1A1NPC1RAB9A | |
| SCHEMBL23012783 | 0.85 | KMO (0.41) | KMOHDAC6ALDH1A1NPC1RAB9A | |
| SCHEMBL23033416 | 0.85 | JMJD6 (0.43) | KMOHDAC6ALDH1A1NPC1RAB9A | |
| SCHEMBL23012716 | 0.84 | KMO (0.38) | KMOHDAC6ALDH1A1NPC1RAB9A | |
| SCHEMBL29479648 | 0.84 | KMO (0.38) | KMOHDAC6ALDH1A1NPC1RAB9A | |
| SCHEMBL28714666 | 0.83 | NPC1 (0.38) | HDAC6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23033561 | 0.82 | PIM1 (0.55) | HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |