Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012095 | 1.00 | MAPT (0.45) | MAPTRAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL23012783 | 0.89 | KMO (0.41) | RAB9ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL29479728 | 0.89 | KMO (0.41) | RAB9ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL29479714 | 0.81 | NPC1 (0.40) | MAPTRAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL23012818 | 0.81 | NPC1 (0.40) | MAPTRAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL28935931 | 0.81 | UTRN (0.37) | MAPTRAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL23012876 | 0.80 | MAPT (0.45) | MAPTRAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL29479616 | 0.80 | MAPT (0.45) | MAPTRAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL23012350 | 0.80 | MAPT (0.47) | MAPTRAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL23012299 | 0.78 | RAB9A (0.69) | MAPTRAB9ASMN1; SMN2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |