SCHEMBL2948040

SCHEMBL2948040

CCC(CC)(O[PH](=O)O)c1ccc(OC)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
ALOX15 P16050 1/20 0.42
APEX1 P27695 1/20 0.42
MAPK1 P28482 1/20 0.42
RECQL P46063 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
NR1I2 O75469 1/20 0.40
MAPT P10636 1/20 0.40
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
AOC3 Q16853 1/20 0.39
IDO1 P14902 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1975027 0.82 ALDH1A1 (0.39) ALDH1A1MAPK1CA1CA2NPC1
SCHEMBL995493 0.81 NPC1 (0.37) ALDH1A1LMNATDP1CA1CA2
SCHEMBL29024520 0.81 HDAC3 (0.43) LMNANPC1EPHX2RAB9ANR1H4
SCHEMBL28391871 0.80 KCNN4 (0.37) ALDH1A1LMNAMAPK1NR1I2MAPT
SCHEMBL995627 0.80 CES2 (0.39) ALDH1A1LMNAALOX15MAPK1MAPT
SCHEMBL8825863 0.80 MAPT (0.45) ALDH1A1LMNAALOX15APEX1MAPK1
SCHEMBL995341 0.80 PLK1 (0.39) ALDH1A1TDP1CA2IDO1PLK1
SCHEMBL1123408 0.80 NPC1 (0.43) ALDH1A1LMNAMAPK1TDP1MAPT
SCHEMBL996408 0.79 MAPK1 (0.40) ALDH1A1LMNAALOX15MAPK1MAPT
SCHEMBL995052 0.78 NR5A1 (0.53) LMNAALOX15HSD17B10MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754403-B2 asymmetric bishydroxy compound having an excellent charge transporting performance as well as excellent solubility in the solvent and compatibility with the resin where no partial crystals are created at the time of film formation, and electrical properties and durability are both excellent SHARP KABUSHIKI KAISHA (JP) 2010-07-13 US disclosed
US-20070207395-A1 Electrophotoconductor and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2007-09-06 US disclosed
US-5608010-A ELECTROGRAPHIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 1997-03-04 US disclosed
US-5488137-A ORGANIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 1996-01-30 US disclosed
US-5322753-A Photosensitivity, durability RICOH COMPANY, LTD. (JP) 1994-06-21 US disclosed