Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30538783 | 0.79 | MEN1 (0.43) | KDM4EL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL30029167 | 0.74 | HCAR3 (0.48) | APAF1POLBMAPT | |
| SCHEMBL30028421 | 0.74 | HCAR3 (0.48) | APAF1POLBMAPT | |
| SCHEMBL29480809 | 0.74 | ADORA2A (0.42) | KDM4EMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL30686398 | 0.69 | GLP1R (0.40) | KDM4EL3MBTL1MEN1TP53PABPC1 | |
| SCHEMBL25405520 | 0.68 | GLP1R (0.41) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL29924416 | 0.68 | MEN1 (0.33) | MEN1TP53PABPC1KMT2AMGAM | |
| SCHEMBL29556035 | 0.68 | MEN1 (0.41) | KDM4EMEN1TP53PABPC1KMT2A | |
| SCHEMBL25405514 | 0.68 | GLP1R (0.41) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL29392201 | 0.68 | GLP1R (0.41) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204415-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022042691-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-03-03 | — | — | WO | disclosed |