Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A3 | Q9HAS3 | 4/20 | 0.60 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.57 |
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | TYMP | P19971 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Curculigoside B SCHEMBL29419859 | 1.00 | SLC28A3 (0.60) | SLC28A3SLC5A1TYRTYMPDYRK1A | |
| Curculigoside A SCHEMBL29419841 | 0.95 | SLC28A3 (0.55) | SLC28A3SLC5A1TYRTYMPDYRK1A | |
| SCHEMBL2962105 | 0.89 | SLC28A3 (0.47) | SLC28A3SLC5A1TYRTYMPDYRK1A | |
| SCHEMBL2948198 | 0.84 | SLC28A3 (0.42) | SLC28A3SLC5A1TYRTYMPDYRK1A | |
| Salireposide SCHEMBL29891482 | 0.81 | TYMP (0.66) | SLC28A3SLC5A1TYRTYMPSLC5A2 | |
| SCHEMBL943236 | 0.81 | SLC28A3 (0.74) | SLC28A3SLC5A1TYRHIF1ASLC5A2 | |
| SCHEMBL940443 | 0.81 | SLC28A3 (0.78) | SLC28A3SLC5A1TYRSNCAHIF1A | |
| SCHEMBL942070 | 0.79 | SLC28A3 (0.71) | SLC28A3SLC5A1TYRKDM4EHIF1A | |
| SCHEMBL940116 | 0.76 | SLC28A3 (0.81) | SLC28A3SLC5A1TYRKDM4ERECQL | |
| SCHEMBL30803061 | 0.76 | SLC28A3 (0.57) | SLC28A3SLC5A1TYRTYMPHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6264994-B1 | Compositions for treating alzheimer's disease and other amyloidoses | UNIVERSITY OF WASHINGTON | 2001-07-24 | — | — | US | disclosed |