Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.46 |
| ▸ | SKP1 | P63208 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482179 | 0.85 | TDP1 (0.39) | CKS1BSKP1SKP2NPSR1MAPT | |
| SCHEMBL29482188 | 0.81 | ANPEP (0.38) | KMT2AALDH1A1 | |
| SCHEMBL29482185 | 0.81 | ANPEP (0.38) | KMT2AALDH1A1 | |
| SCHEMBL17155011 | 0.79 | MAPK8 (0.37) | KLK5NPR3 | |
| SCHEMBL17155379 | 0.78 | MAPK8 (0.37) | NPSR1MAPTTDP1KDM4EPOLB | |
| SCHEMBL6503512 | 0.77 | SYK (0.41) | CKS1BSKP1SKP2IDO1NPSR1 | |
| SCHEMBL18878470 | 0.76 | CA1 (0.49) | IDO1NPSR1MAPTTDP1MEN1 | |
| SCHEMBL14561127 | 0.74 | SYK (0.61) | IDO1MAPTALDH1A1KLK5CTSS | |
| SCHEMBL11919227 | 0.73 | MEN1 (0.50) | IDO1NPSR1TDP1MEN1KMT2A | |
| SCHEMBL5926274 | 0.73 | CTSS (0.57) | IDO1POLBKLK5CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481814-B1 | TETRAHYDRONAPHTHYRIDINEPENTANAMIDE INTEGRIN ANTAGONISTS | UNIV ROCKEFELLER (US) | 2022-04-27 | — | — | EP | disclosed |