Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482185 | 1.00 | ANPEP (0.38) | ANPEPWNT3ACYP26A1AXLKMT2A | |
| SCHEMBL29482182 | 0.81 | CKS1B (0.46) | KMT2AALDH1A1 | |
| SCHEMBL20027765 | 0.74 | MAPT (0.41) | WNT3ACYP26A1ATMALDH1A1 | |
| SCHEMBL6494101 | 0.71 | ALDH1A1 (0.41) | KMT2AHDAC1HDAC6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7215995 | 0.70 | ALDH1A1 (0.40) | KMT2AHDAC1HDAC6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7447537 | 0.70 | ALDH1A1 (0.40) | KMT2AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL13606447 | 0.69 | ALDH1A1 (0.40) | KMT2AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL25867792 | 0.68 | SMN1; SMN2 (0.48) | KMT2AHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL22029461 | 0.68 | KYNU (0.60) | ALDH1A1 | |
| SCHEMBL13887440 | 0.68 | KYNU (0.60) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481814-B1 | TETRAHYDRONAPHTHYRIDINEPENTANAMIDE INTEGRIN ANTAGONISTS | UNIV ROCKEFELLER (US) | 2022-04-27 | — | — | EP | disclosed |