SCHEMBL29482240

SCHEMBL29482240

COC(C(=O)Cl)=C(OC)c1ccccc1OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.51
STAT3 P40763 1/20 0.49
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
KCNK3 O14649 1/20 0.46
KCNK9 Q9NPC2 1/20 0.46
HPGD P15428 2/20 0.45
GAA P10253 2/20 0.45
MAPT P10636 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
TP53 P04637 1/20 0.45
GLA P06280 1/20 0.45
FAAH O00519 1/20 0.44
CNR2 P34972 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10608286 1.00 CTSD (0.51) CTSDSTAT3NPC1RAB9ALMNA
SCHEMBL540772 0.85 STAT3 (0.54) CTSDSTAT3NPC1RAB9ASMN1; SMN2
SCHEMBL31022703 0.85 CTSD (0.53) CTSDSTAT3NPC1RAB9ALMNA
SCHEMBL9134542 0.85 CTSD (0.53) CTSDSTAT3NPC1RAB9ALMNA
SCHEMBL28622158 0.83 CTSD (0.56) CTSDSTAT3NPC1RAB9ALMNA
Hydrochloric Acid SCHEMBL11853756 0.83 STAT3 (0.53) CTSDSTAT3NPC1RAB9ASMN1; SMN2
SCHEMBL30664617 0.78 HPGD (0.47) CTSDSTAT3NPC1RAB9ASMN1; SMN2
SCHEMBL27804003 0.77 CTSD (0.55) CTSDSTAT3NPC1RAB9ALMNA
SCHEMBL431 0.76 CTSD (0.63) CTSDSTAT3NPC1RAB9ALMNA
SCHEMBL29392137 0.76 CTSD (0.63) CTSDSTAT3NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112670722-B Insulated wire connecting device 国网浙江省电力有限公司开化县供电公司 2022-03-25 CN disclosed