SCHEMBL431

SCHEMBL431

COc1ccccc1C(=O)Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.63
STAT3 P40763 1/20 0.55
HTT P42858 2/20 0.53
NPC1 O15118 3/20 0.53
RAB9A P51151 2/20 0.53
ABCG2 Q9UNQ0 1/20 0.53
KCNK3 O14649 1/20 0.51
KCNK9 Q9NPC2 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
LMNA P02545 1/20 0.51
HPGD P15428 3/20 0.50
ALDH1A1 P00352 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
TP53 P04637 1/20 0.50
GLA P06280 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392137 1.00 CTSD (0.63) CTSDSTAT3HTTNPC1RAB9A
Benzene SCHEMBL28557251 0.86 CTSD (0.54) CTSDSTAT3HTTNPC1RAB9A
SCHEMBL7430967 0.84 CTSD (0.51) CTSDSTAT3HTTNPC1RAB9A
SCHEMBL27804003 0.83 CTSD (0.55) CTSDSTAT3HTTNPC1RAB9A
SCHEMBL322168 0.82 CTSD (0.62) CTSDSTAT3HTTNPC1RAB9A
SCHEMBL3357655 0.82 ALDH1A1 (0.52) CTSDHTTSMN1; SMN2HPGDALDH1A1
SCHEMBL29658169 0.82 CTSD (0.62) CTSDSTAT3HTTNPC1RAB9A
SCHEMBL10736102 0.82 CA1 (0.55) CTSDSTAT3HTTNPC1RAB9A
SCHEMBL870484 0.82 CTSD (0.62) CTSDSTAT3HTTNPC1RAB9A
SCHEMBL9357148 0.82 JAK2 (0.56) CTSDHTTNPC1RAB9AKCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2739 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof ISP INVESTMENTS LLC (US) 2026-02-17 US claimed
US-20250304541-A1 METHYLENE BLUE HAVING A REDUCED CONTENT OF N-NITROSO-AZURE B IMPURITY AND PROCESS FOR OBTAINING THE SAME Icrom S.R.L. (IT) 2025-10-02 US claimed
CN-115586282-B Quantitative method for trace silicon hydroxyl in MQ silicon resin 杭州师范大学 2025-04-15 CN claimed
CN-119569803-A Method for preparing high-purity estetrol 秦皇岛紫竹药业有限公司 2025-03-07 CN claimed
WO-2024250573-A1 REVERSE OSMOSIS MEMBRANE PREPARATION METHOD AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY 沃顿科技股份有限公司 2024-12-12 WO claimed
CN-119098067-A Method for producing reverse osmosis membrane and reverse osmosis membrane produced thereby 沃顿科技股份有限公司 2024-12-10 CN claimed
CN-118955564-A DOPO phosphoramide derivative flame retardant, preparation method thereof and application thereof in waterborne polyurethane 浙江理工大学 2024-11-15 CN claimed
CN-115703737-B Hydroxypyridones compound and application thereof as antibiotic sensitizer for overcoming bacterial biomembrane resistance 暨南大学 2024-09-24 CN claimed
CN-117050007-A Compound based on urea structure, preparation method thereof and application thereof in molluscicide 云南大学 2023-11-14 CN claimed
CN-112358487-B Lappaconitine derivative, and preparation method and application thereof 中国科学院新疆理化技术研究所 2023-08-25 CN claimed
CN-1222131-A Acylation method for aromatic compound RHONE POULENC CHIMIE (FR) 1999-07-07 CN claimed
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
EP-0639559-A1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM AND HAAS COMPANY (US) 1995-02-22 EP claimed
US-5334724-A Preparation of substituted 2-chloropyridines BAYER AKTIENGESELLSCHAFT (DE) 1994-08-02 US claimed
EP-0438691-B1 Process for the preparation of substituted 2-chloropyridines BAYER AG (DE) 1994-02-16 EP claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US claimed
EP-0438691-A1 Process for the preparation of substituted 2-chloropyridines BAYER AG (DE) 1991-07-31 EP claimed
US-4620009-A CATALYTIC REDUCTION OF IMIDAZOLIN ONE DERIVATIVE CYANAMID AGRICULTURAL DE PUERTO RICO, INC. (US) 1986-10-28 US claimed
EP-0168733-A2 Process for the preparation of quinolinone and naphthyridoncarboxylic acids BAYER AG (DE) 1986-01-22 EP claimed