Sugi Predict

Sugi Predict / Compounds / SCHEMBL29482473

SCHEMBL29482473

SCHEMBL29482473

CC(=O)N[C@H]1CSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)NC(=O)CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCC(=O)O)NC1=O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ F11 P03951 1/20 0.56
▸ IL23R Q5VWK5 17/20 0.56
▸ PRLHR P49683 1/20 0.54
▸ GLP1R P43220 1/20 0.53
▸ GCGR P47871 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392338 0.93 TSLP (0.57) F11IL23RPRLHRGLP1RGCGR
SCHEMBL29476611 0.92 TSLP (0.54) F11IL23RPRLHR
SCHEMBL29482514 0.89 TSLP (0.58) F11PRLHRGLP1RGCGR
SCHEMBL29482547 0.89 MC5R (0.54) F11IL23R
SCHEMBL29476446 0.87 MC4R (0.52) F11IL23R
SCHEMBL30773905 0.86 TSLP (0.51) F11IL23RPRLHR
SCHEMBL14550392 0.85 TSLP (0.54) F11IL23RGLP1R
SCHEMBL29482496 0.84 MC4R (0.48) F11IL23R
SCHEMBL29482472 0.84 KRAS (0.50) F11
SCHEMBL29482437 0.83 CXCR4 (0.47) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711004-A2 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS Rhythm Pharmaceuticals, Inc. (US) 2026-03-18 — — EP disclosed
CN-120152725-A Methods of treating obesity using MC4R agonists 节奏制药公司 2025-06-13 — — CN disclosed
EP-3988108-A1 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR-ASSOCIATED DISORDERS IN HETEROZYGOUS CARRIERS Rhythm Pharmaceuticals, Inc. (US) 2022-04-27 — — EP disclosed