SCHEMBL2948401

SCHEMBL2948401

[CH]1C(CC2=Cc3ccccc3[CH]2)=Cc2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.31
CALM1 P0DP23 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216993 0.85 CALM1 (0.48) CALM1
SCHEMBL1135141 0.83 GAA (0.31)
SCHEMBL6896931 0.79
SCHEMBL2967523 0.79
SCHEMBL27932983 0.79 CALM1 (0.41) CALM1
SCHEMBL27932963 0.79 CALM1 (0.41) CALM1
SCHEMBL27933181 0.79 CALM1 (0.41) CALM1
SCHEMBL27948762 0.79 CALM1 (0.41) CALM1
SCHEMBL27933016 0.79 CALM1 (0.41) CALM1
SCHEMBL27948582 0.79 CALM1 (0.41) CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100069598-A1 RING-OPENING POLYMERIZATION OF CYCLIC ESTERS, POLYESTERS FORMED THEREBY, AND ARTICLES COMPRISING THE POLYESTERS NATIONAL SCIENCE FOUNDATION 2010-03-18 US disclosed
US-7671140-B2 Ring-opening polymerization of cyclic esters, polyesters formed thereby, and articles comprising the polyesters THE UNIVERSITY OF CONNECTICUT (US) 2010-03-02 US disclosed
WO-2008124035-A2 RING-OPENING POLYMERIZATION OF CYCLIC ESTERS, POLYESTERS FORMED THEREBY, AND ARTICLES COMPRISING THE POLYESTERS UNIVERSITY OF CONNECTICUT (US) 2008-10-16 WO disclosed
US-20080249255-A1 RING-OPENING POLYMERIZATION OF CYCLIC ESTERS, POLYESTERS FORMED THEREBY, AND ARTICLES COMPRISING THE POLYESTERS NATIONAL SCIENCE FOUNDATION 2008-10-09 US disclosed
EP-1954724-A1 SYNDIOTACTIC PROPYLENE ELASTOMERS ExxonMobil Chemical Patents Inc. (US) 2008-08-13 EP disclosed
WO-2007061525-A1 SYNDIOTACTIC PROPYLENE ELASTOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-31 WO disclosed
EP-1558655-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM Exxonmobil Chemical Patents Inc. (US) 2005-08-03 EP disclosed
WO-2004046214-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-06-03 WO disclosed
US-6100352-A USING A CATALYST CONSISTING OF A TRANSITION METAL COMPOUND, A COMPOUND CAPABLE OF FORMING AN IONIC COMPOUND BY REACTING WITH THE TRANSITION METAL COMPOUND OR AN OXYGEN-CONTAINING COMPOUND SUCH AS ALUMINOXANE IDEMITSU KOSAN CO., LTD. (JP) 2000-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080249255-A1 RING-OPENING POLYMERIZATION OF CYCLIC ESTERS, POLYESTERS FORMED THEREBY, AND ARTICLES COMPRISING THE POLYESTERS PUF60, COASY, TECR HSPA5 1583/4885CALM1 4849/4885
US-20100069598-A1 RING-OPENING POLYMERIZATION OF CYCLIC ESTERS, POLYESTERS FORMED THEREBY, AND ARTICLES COMPRISING THE POLYESTERS PUF60, COASY, TECR HSPA5 1583/4885CALM1 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.