⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24777662 | 0.75 | — | — | |
| SCHEMBL30874783 | 0.72 | MEN1 (0.35) | — | |
| SCHEMBL22792947 | 0.71 | — | — | |
| SCHEMBL4037370 | 0.69 | — | — | |
| SCHEMBL29809502 | 0.68 | CYP2D6 (0.33) | — | |
| SCHEMBL24783963 | 0.68 | MEN1 (0.37) | — | |
| SCHEMBL15120307 | 0.68 | HTR5A (0.35) | — | |
| SCHEMBL22792847 | 0.67 | — | — | |
| SCHEMBL25151176 | 0.67 | — | — | |
| SCHEMBL29820325 | 0.66 | MAOA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111763214-B | Preparation method of icotinib | 苏州富士莱医药股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| WO-2022032943-A1 | PREPARATION METHOD FOR ICOTINIB | 苏州富士莱医药股份有限公司 | 2022-02-17 | — | — | WO | claimed |
| CN-111763214-B | Preparation method of icotinib | 苏州富士莱医药股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-111763214-B | Preparation method of icotinib | 苏州富士莱医药股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| WO-2022032943-A1 | PREPARATION METHOD FOR ICOTINIB | 苏州富士莱医药股份有限公司 | 2022-02-17 | — | — | WO | disclosed |