Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31090324 | 0.87 | GAA (0.62) | HPGDRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL4391461 | 0.83 | HPGD (0.62) | MAPK1HPGDRAB9ANPC1KMT2A | |
| SCHEMBL360387 | 0.82 | NPC1 (0.70) | HPGDRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL526026 | 0.82 | ALDH1A1 (0.70) | HPGDRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL16587385 | 0.82 | ALDH1A1 (0.78) | MAPK1RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL8167087 | 0.82 | CYP1A2 (0.85) | HPGDRAB9ANPC1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3718186 | 0.81 | ALDH1A1 (0.71) | MAPK1RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL4105580 | 0.80 | NPC1 (0.58) | HPGDRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL6814406 | 0.79 | CYP1A2 (0.69) | HPGDRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL455626 | 0.79 | HPGD (0.70) | HPGDRAB9ANPC1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022055940-A1 | VISTA INHIBITORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-03-17 | — | — | WO | disclosed |