Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | ENTPD5 | O75356 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18799413 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL22922106 | 0.80 | HSD11B1 (0.64) | ALDH1A1CYP3A4PTPN1F10HSD11B1 | |
| SCHEMBL24721979 | 0.80 | F10 (0.39) | PTPN1F10HSD11B1MEN1KMT2A | |
| SCHEMBL13401505 | 0.80 | HSD11B1 (0.64) | ALDH1A1CYP3A4PTPN1F10HSD11B1 | |
| SCHEMBL22922195 | 0.80 | HSD11B1 (0.64) | ALDH1A1CYP3A4PTPN1F10HSD11B1 | |
| SCHEMBL22922186 | 0.79 | F10 (0.66) | CYP2C9PTPN1F10HSD11B1MEN1 | |
| SCHEMBL22922196 | 0.79 | F10 (0.66) | CYP2C9PTPN1F10HSD11B1MEN1 | |
| SCHEMBL31571702 | 0.78 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL3493335 | 0.73 | HSD11B1 (0.56) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL3490504 | 0.73 | HSD11B1 (0.44) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986205-B | Isosteviol derivative and preparation method and application thereof | 广东工业大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-117986205-A | Isosteviol derivative and preparation method and application thereof | 广东工业大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-113105348-B | Isosteviol derivative and preparation method and application thereof | 广东工业大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-114249650-B | Steviol derivative, preparation method thereof and application thereof in preparing heart protection medicine | 广东工业大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114133327-B | Steviol derivative and preparation method and application thereof | 广东工业大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-114249650-A | Steviol derivative, preparation method thereof and application thereof in preparing heart protection medicine | 广东工业大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-114133327-A | Steviol derivative and preparation method and application thereof | 广东工业大学 | 2022-03-04 | — | — | CN | disclosed |