Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746344 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1CREBBPF3 | |
| SCHEMBL30666298 | 0.91 | GAA (0.39) | SMN1; SMN2RAB9ANPC1F3KCNA5 | |
| SCHEMBL29615863 | 0.91 | GAA (0.39) | SMN1; SMN2RAB9ANPC1F3KCNA5 | |
| SCHEMBL28746342 | 0.91 | GAA (0.39) | SMN1; SMN2RAB9ANPC1F3KCNA5 | |
| SCHEMBL29486081 | 0.85 | GPR52 (0.36) | SMN1; SMN2RAB9ANPC1F3KCNA5 | |
| SCHEMBL22899346 | 0.85 | GPR52 (0.36) | SMN1; SMN2RAB9ANPC1F3KCNA5 | |
| SCHEMBL21617101 | 0.78 | KMT2A (0.43) | SMN1; SMN2RAB9ANPC1F3KCNA5 | |
| SCHEMBL31611960 | 0.78 | KMT2A (0.43) | SMN1; SMN2RAB9ANPC1F3KCNA5 | |
| SCHEMBL22899612 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2RAB9ANPC1F3KCNA5 | |
| SCHEMBL29486220 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2RAB9ANPC1F3KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423741-B | aryl-N-aryl derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2023-11-07 | — | — | CN | disclosed |
| EP-3999493-A1 | ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION | ABIVAX (FR) | 2022-05-25 | — | — | EP | disclosed |
| CN-114423741-A | aryl-N-aryl derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2022-04-29 | — | — | CN | disclosed |