Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30666298 | 1.00 | GAA (0.39) | GAAHPGDGPR52KCNA5NPC1 | |
| SCHEMBL28746342 | 1.00 | GAA (0.39) | GAAHPGDGPR52KCNA5NPC1 | |
| SCHEMBL28746344 | 0.91 | SMN1; SMN2 (0.41) | GAAHPGDGPR52KCNA5NPC1 | |
| SCHEMBL29486146 | 0.91 | SMN1; SMN2 (0.41) | GAAHPGDGPR52KCNA5NPC1 | |
| SCHEMBL29486081 | 0.84 | GPR52 (0.36) | GAAHPGDGPR52KCNA5NPC1 | |
| SCHEMBL22899346 | 0.84 | GPR52 (0.36) | GAAHPGDGPR52KCNA5NPC1 | |
| SCHEMBL28746339 | 0.77 | KCNA5 (0.37) | HPGDGPR52KCNA5NPC1SMN1; SMN2 | |
| SCHEMBL22899408 | 0.77 | HPGD (0.35) | HPGDGPR52KCNA5NPC1SMN1; SMN2 | |
| SCHEMBL31611960 | 0.76 | KMT2A (0.43) | HPGDKCNA5NPC1SMN1; SMN2RAB9A | |
| SCHEMBL21617101 | 0.76 | KMT2A (0.43) | HPGDKCNA5NPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999493-A1 | ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION | ABIVAX (FR) | 2022-05-25 | — | — | EP | disclosed |