Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL1784551 | 1.00 | CSNK1E (0.46) | CSNK1EMMP1MMP9MMP13CNR2 | |
| Ammonia Solution, Strong SCHEMBL297223 | 1.00 | CSNK1E (0.46) | CSNK1EMMP1MMP9MMP13CNR2 | |
| Ammonia Solution, Strong SCHEMBL1840232 | 1.00 | CSNK1E (0.46) | CSNK1EMMP1MMP9MMP13CNR2 | |
| Ammonia Solution, Strong SCHEMBL5183320 | 1.00 | CSNK1E (0.46) | CSNK1EMMP1MMP9MMP13CNR2 | |
| Ammonia Solution, Strong SCHEMBL875995 | 1.00 | CSNK1E (0.46) | CSNK1EMMP1MMP9MMP13CNR2 | |
| Ammonia Solution, Strong SCHEMBL5826088 | 1.00 | CSNK1E (0.46) | CSNK1EMMP1MMP9MMP13CNR2 | |
| Ammonia Solution, Strong SCHEMBL10532522 | 0.98 | CSNK1E (0.44) | CSNK1EMMP1MMP9MMP13CNR2 | |
| SCHEMBL2788441 | 0.98 | CSNK1E (0.47) | CSNK1EMMP1MMP9MMP13CNR2 | |
| Ammonia Solution, Strong SCHEMBL11610968 | 0.94 | CTSK (0.40) | CSNK1EMMP1MMP9MMP13CNR2 | |
| Ammonia Solution, Strong SCHEMBL4446130 | 0.85 | CSNK1E (0.43) | CSNK1EMMP1MMP9MMP13CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110337467-B | Method for preparing colorant composition and colorant composition prepared thereby | 株式会社LG化学 | 2021-08-27 | — | — | CN | disclosed |
| US-8940889-B2 | Process for producing benzo [b] [1,4] diazepine-2,4-dione compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-01-27 | — | — | US | disclosed |
| US-8796447-B2 | Process for producing benzo[B][1,4]diazepine-2,4-dione compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20140194621-A1 | PROCESS FOR PRODUCING BENZO [B] [1,4] DIAZEPINE-2, 4-DIONE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-07-10 | — | — | US | disclosed |
| EP-1727782-B1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 2012-08-22 | — | — | EP | disclosed |
| EP-2468733-A1 | PROCESS FOR PRODUCING BENZO[B][1,4]DIAZEPINE-2,4-DIONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-20120149899-A1 | PROCESS FOR PRODUCING BENZO[B][1,4]DIAZEPINE-2,4-DIONE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
| US-7750156-B2 | Method of producing aminophenol compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-07-06 | — | — | US | disclosed |
| US-20070219374-A1 | Method of Producing Aminophenol Compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1727782-A1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005092832-A1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149899-A1 | PROCESS FOR PRODUCING BENZO[B][1,4]DIAZEPINE-2,4-DIONE COMPOUND | KCNH1, KCNB2, KCNJ2 | CSNK1E 3026/4885MMP1 2796/4885MMP9 2089/4885 |
| US-20070219374-A1 | Method of Producing Aminophenol Compounds | PAH, CYP1A1, CYP1B1 | CSNK1E 1611/4885MMP1 3677/4885MMP9 4199/4885 |
| US-20140194621-A1 | PROCESS FOR PRODUCING BENZO [B] [1,4] DIAZEPINE-2, 4-DIONE COMPOUND | KCNH1, KCNB2, KCNB1 | CSNK1E 3096/4885MMP1 3363/4885MMP9 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.