Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21754369 | 0.76 | NR2E1 (0.75) | NR2E1KDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL4084559 | 0.75 | SSTR3 (0.50) | — | |
| SCHEMBL14584257 | 0.73 | BRD3 (0.57) | CHRNA7HPGDADRA1DADRA1AADRA1B | |
| SCHEMBL5229700 | 0.72 | MEN1 (0.47) | NR2E1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL7088610 | 0.71 | BRD3 (0.67) | MEN1KMT2AHSD17B10CHRNA7ADRA1D | |
| SCHEMBL18932895 | 0.71 | TAAR1 (0.49) | NR2E1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL10749016 | 0.71 | MEN1 (0.45) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL18212309 | 0.71 | KDM4E (0.60) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL18212307 | 0.71 | KDM4E (0.60) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL24830799 | 0.70 | ADRA1D (0.46) | MEN1KMT2AKDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022046605-A1 | COMPOSITIONS AND METHODS FOR G-PROTEIN-COUPLED RECEPTOR 44 DETECTION | CITY OF HOPE (US) | 2022-03-03 | — | — | WO | disclosed |