Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RB1 | P06400 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076324 | 0.78 | NR2E1 (0.54) | MEN1KMT2ACHRNA7KDM4EHSD17B10 | |
| SCHEMBL28258680 | 0.77 | CYP2D6 (0.53) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL10743387 | 0.72 | ADRA1D (0.45) | MEN1KMT2AKDM4ETSHRHSD17B10 | |
| SCHEMBL29486335 | 0.72 | NR2E1 (0.51) | MEN1KMT2ACHRNA7KDM4ETSHR | |
| SCHEMBL2515919 | 0.71 | NR2E1 (0.67) | MEN1KMT2ACHRNA7HSD17B10RB1 | |
| SCHEMBL1877922 | 0.71 | BRD3 (0.67) | MEN1KMT2ACHRNA7HSD17B10RB1 | |
| SCHEMBL18212309 | 0.71 | KDM4E (0.60) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL18212307 | 0.71 | KDM4E (0.60) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL10743390 | 0.70 | ADRA1D (0.43) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL26179056 | 0.69 | KDM4E (0.61) | MEN1KMT2AKDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412336-A4 | PEPTOID COMPOUNDS | UNIV WOLLONGONG (AU) | 2007-08-29 | — | — | EP | disclosed |
| EP-1412336-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003002545-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2003-01-09 | — | — | WO | disclosed |