SCHEMBL2948696

SCHEMBL2948696

CCOC(OCC)C(=O)O[SiH3]

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
LMNA P02545 2/20 0.38
HSD17B10 Q99714 1/20 0.38
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
TRPA1 O75762 1/20 0.33
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7054488 0.80
SCHEMBL11696005 0.80 ALDH1A1 (0.45) ALDH1A1LMNATSHRHCAR2
SCHEMBL7059086 0.78
SCHEMBL7058932 0.78 ALDH1A1 (0.35) ALDH1A1LMNAHSD17B10THRBALOX15
SCHEMBL143815 0.78 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10THRBALOX15
SCHEMBL22207048 0.78 SOAT1 (0.46) ALDH1A1LMNAHSD17B10THRBALOX15
SCHEMBL30600798 0.76 SOAT1 (0.43) ALDH1A1LMNAHSD17B10THRBALOX15
SCHEMBL6437698 0.76 MGAM (0.43) ALDH1A1LMNAHSD17B10THRBALOX15
SCHEMBL11217411 0.76 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10THRBALOX15
SCHEMBL3298069 0.74 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10THRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661960-B1 COATING COMPOSITION AND LOW DIELECTRIC SILICEOUS MATERIAL PRODUCED BY USING SAME AZ ELECTRONIC MATERIALS USA (US) 2012-07-25 EP claimed
US-7754003-B2 Coating composition and low dielectric siliceous material produced by using same AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-07-13 US claimed
EP-1661960-B1 COATING COMPOSITION AND LOW DIELECTRIC SILICEOUS MATERIAL PRODUCED BY USING SAME AZ ELECTRONIC MATERIALS USA (US) 2012-07-25 EP disclosed
US-7754003-B2 Coating composition and low dielectric siliceous material produced by using same AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-07-13 US disclosed
US-20060246303-A1 Coating composition and low dielectric siliceous material produced by using same MERCK PATENT GMBH (DE) 2006-11-02 US disclosed
EP-1342742-B1 Room temperature curable polysiloxane compositions HANSE CHEMIE AG (DE) 2006-08-02 EP disclosed
EP-1661960-A1 COATING COMPOSITION AND LOW DIELECTRIC SILICEOUS MATERIAL PRODUCED BY USING SAME AZ Electronic Materials USA Corp. (US) 2006-05-31 EP disclosed
EP-1342742-A1 Room temperature curable polysiloxane compositions hanse chemie AG (DE) 2003-09-10 EP disclosed
EP-1085022-A1 A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds Dow Corning Asia, Ltd. (JP) 2001-03-21 EP disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
US-6060620-A Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds DOW CORNING ASIA, LTD. (JP) 2000-05-09 US disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed