Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22207048 | 0.97 | SOAT1 (0.46) | SOAT1ALDH1A1LMNAHSD17B10THRB | |
| SCHEMBL4405369 | 0.84 | SOAT1 (0.40) | SOAT1ALDH1A1LMNAHSD17B10THRB | |
| SCHEMBL143815 | 0.80 | ALDH1A1 (0.50) | SOAT1ALDH1A1LMNAHSD17B10THRB | |
| SCHEMBL7930920 | 0.79 | ALDH1A1 (0.42) | SOAT1ALDH1A1LMNATDP1TSHR | |
| SCHEMBL6437698 | 0.78 | MGAM (0.43) | SOAT1ALDH1A1LMNAHSD17B10THRB | |
| SCHEMBL11217411 | 0.78 | ALDH1A1 (0.48) | SOAT1ALDH1A1LMNAHSD17B10THRB | |
| SCHEMBL2948696 | 0.76 | ALDH1A1 (0.39) | SOAT1ALDH1A1LMNAHSD17B10THRB | |
| SCHEMBL3298069 | 0.76 | ALDH1A1 (0.39) | SOAT1ALDH1A1LMNAHSD17B10THRB | |
| SCHEMBL28762237 | 0.76 | ALDH1A1 (0.39) | SOAT1ALDH1A1LMNAHSD17B10THRB | |
| SCHEMBL6437690 | 0.76 | ALDH1A1 (0.39) | SOAT1ALDH1A1LMNAHSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024411-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-110709392-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |