SCHEMBL29487148

SCHEMBL29487148

Cn1cc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)cn1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MET P08581 19/20 0.57
KDR P35968 14/20 0.57
KIT P10721 1/20 0.48
MST1R Q04912 9/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2530838 0.86 MET (0.48) METKDRMST1R
SCHEMBL2670877 0.85 MET (0.46) METKDRMST1R
SCHEMBL2539404 0.85 MET (0.47) METKDRMST1R
SCHEMBL10223899 0.83 MET (0.44) METKDRKIT
SCHEMBL16187724 0.82 MET (0.52) METKDRMST1R
SCHEMBL3568097 0.82 MET (0.51) METKDRMST1R
SCHEMBL2285100 0.82 MET (0.49) METKDRMST1R
SCHEMBL29487137 0.82 MET (0.63) METKDRMST1R
SCHEMBL306299 0.82 MET (0.63) METKDRMST1R
SCHEMBL25360226 0.81 AXL (0.41) METKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114206883-A Oxopyridine fused ring derivative and pharmaceutical composition comprising the same 伟迈可生物有限公司 2022-03-18 CN disclosed