Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.56 |
| ▸ | KDR | P35968 | 17/20 | 0.56 |
| ▸ | MST1R | Q04912 | 4/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2285100 | 0.86 | MET (0.49) | METKDRMST1R | |
| SCHEMBL14987889 | 0.85 | MET (0.42) | METKDRMST1R | |
| SCHEMBL14987891 | 0.84 | MET (0.43) | METKDRMST1R | |
| SCHEMBL27836928 | 0.84 | MET (0.42) | METKDRMST1RAURKAFPR1 | |
| SCHEMBL10223899 | 0.83 | MET (0.44) | METKDR | |
| SCHEMBL14230708 | 0.83 | MET (0.44) | METKDRMST1RAURKAFPR1 | |
| SCHEMBL306299 | 0.82 | MET (0.63) | METKDRMST1RAURKAFPR1 | |
| SCHEMBL29487137 | 0.82 | MET (0.63) | METKDRMST1RAURKAFPR1 | |
| SCHEMBL2602368 | 0.81 | MET (0.42) | METKDRMST1R | |
| SCHEMBL14817529 | 0.81 | MET (0.49) | METKDRMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206883-A | Oxopyridine fused ring derivative and pharmaceutical composition comprising the same | 伟迈可生物有限公司 | 2022-03-18 | — | — | CN | disclosed |