Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL10456148 | 1.00 | — | — | |
| Trifluoroacetic Acid SCHEMBL11398401 | 0.96 | — | — | |
| Trifluoroacetic Acid SCHEMBL474 | 0.95 | — | — | |
| Trifluoroacetic Acid SCHEMBL30657022 | 0.95 | — | — | |
| Trifluoroacetic Acid SCHEMBL4598430 | 0.95 | — | — | |
| Trifluoroacetic Acid SCHEMBL7814389 | 0.95 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1TSHRTHRBTP53 | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.95 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1TSHRTHRBTP53 | |
| Trifluoroacetic Acid SCHEMBL25297651 | 0.91 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1TSHRTHRBTP53 | |
| Trifluoroacetic Acid SCHEMBL22712611 | 0.91 | — | — | |
| Trifluoroacetic Acid SCHEMBL20541014 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117677606-A | 2-carboxy-indole inhibitors of metallo-beta-lactamase | 牛津大学创新有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-115919996-A | Adiponectin peptidomimetics for the treatment of ophthalmic diseases | 雅利斯塔制药公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115151540-A | Polyheterocyclic compounds as METTL3 inhibitors | 风暴治疗有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-107530396-B | Adiponectin peptidomimetics for the treatment of ophthalmic diseases | 雅利斯塔制药公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114286711-A | Bicyclic heterocyclic compounds as inhibitors of BCDIN3D activity | 风暴治疗有限公司 | 2022-04-05 | — | — | CN | disclosed |