SCHEMBL29487288

SCHEMBL29487288

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ENPEP Q07075 5/20 0.48
▸ BACE1 P56817 4/20 0.46
▸ GRIN2D O15399 1/20 0.44
▸ GRIN3B O60391 1/20 0.44
▸ GRIN1 Q05586 1/20 0.44
▸ GRIN2A Q12879 1/20 0.44
▸ GRIN2B Q13224 1/20 0.44
▸ GRIN2C Q14957 1/20 0.44
▸ GRIN3A Q8TCU5 1/20 0.44
▸ F2 P00734 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29514212 0.93 BACE1 (0.49) ENPEPBACE1GRIN2DGRIN3BGRIN1
SCHEMBL31369342 0.93 ENPEP (0.53) ENPEPBACE1F2
SCHEMBL10375379 0.91 ENPEP (0.54) ENPEPBACE1F2
SCHEMBL10375374 0.91 ENPEP (0.54) ENPEPBACE1F2
SCHEMBL10374382 0.90 ENPEP (0.53) ENPEPBACE1F2
SCHEMBL10374381 0.90 ENPEP (0.53) ENPEPBACE1F2
SCHEMBL30627971 0.90 FOLH1 (0.50) BACE1
SCHEMBL31369290 0.89 ENPEP (0.46) ENPEPBACE1GRIN2DGRIN3BGRIN1
SCHEMBL30047082 0.89 ENPEP (0.56) ENPEPBACE1
SCHEMBL827833 0.88 NMT2 (0.45) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388650-A1 OLIGO-TRAP FUSION PROTEINS (OFPs) AND USES THEREOF ENOSI THERAPEUTICS CORP (US) 2025-12-25 — — US disclosed
WO-2024186690-A2 OLIGO-TRAP FUSION PROTEINS (OFPS) AND USES THEREOF ENOSI THERAPEUTICS CORPORATION (US) 2024-09-12 — — WO disclosed
CN-116847887-A Methods and compositions for treating autoimmune diseases and cancers 伊诺西治疗公司 2023-10-03 — — CN disclosed
WO-2023168426-A1 COMPOSITIONS AND CELLS CONTAINING MIXTURES OF OLIGO-TRAP FUSION PROTEINS (OFPS) AND USES THEREOF ENOSI THERAPEUTICS CORPORATION (US) 2023-09-07 — — WO disclosed
EP-4204094-A1 METHODS AND COMPOSITIONS TO TREAT AUTOIMMUNE DISEASES AND CANCER ENOSI THERAPEUTICS CORPORATION (US) 2023-07-05 — — EP disclosed
US-20220288226-A1 METHODS AND COMPOSITIONS TO TREAT AUTOIMMUNE DISEASES AND CANCER ENOSI THERAPEUTICS CORPORATION 2022-09-15 — — US disclosed
WO-2022047243-A1 METHODS AND COMPOSITIONS TO TREAT AUTOIMMUNE DISEASES AND CANCER ENOSI LIFE SCIENCES CORP. (US) 2022-03-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388650-A1 OLIGO-TRAP FUSION PROTEINS (OFPs) AND USES THEREOF TNFSF11, TNFRSF9, FCER2 ENPEP 177/4885BACE1 3817/4885GRIN2D 4348/4885
US-20220288226-A1 METHODS AND COMPOSITIONS TO TREAT AUTOIMMUNE DISEASES AND CANCER TNFRSF1A, TNFRSF9, CD40 ENPEP 2144/4885BACE1 4312/4885GRIN2D 3186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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