Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5290305 | 1.00 | HTR2C (0.62) | HTR2CDRD2MEN1KMT2AMAP1LC3B | |
| SCHEMBL26918402 | 0.95 | HTR2C (0.57) | HTR2CDRD2MEN1KMT2AMAP1LC3B | |
| SCHEMBL12667873 | 0.90 | ADRA1A (0.55) | HTR2CDRD2MEN1KMT2AMAP1LC3B | |
| SCHEMBL30129583 | 0.90 | ADRA1A (0.55) | HTR2CDRD2MEN1KMT2AMAP1LC3B | |
| SCHEMBL12635239 | 0.90 | ADRA1A (0.55) | HTR2CDRD2MEN1KMT2AMAP1LC3B | |
| SCHEMBL12635245 | 0.90 | ADRA1A (0.55) | HTR2CDRD2MEN1KMT2AMAP1LC3B | |
| SCHEMBL1515163 | 0.85 | HTR2C (0.75) | HTR2CDRD2MEN1KMT2AMAP1LC3B | |
| SCHEMBL7208759 | 0.82 | PTGDR2 (0.44) | HTR2CDRD2MEN1KMT2AADRA1D | |
| SCHEMBL34463201 | 0.81 | HTR2C (0.53) | HTR2CDRD2MEN1KMT2AMAP1LC3B | |
| SCHEMBL824116 | 0.81 | HTR2C (0.53) | HTR2CDRD2MEN1KMT2AMAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181136-A | Substituted piperidine compounds and uses thereof | 武田药品工业株式会社 | 2022-03-15 | — | — | CN | disclosed |