Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | DTYMK | P23919 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293089 | 1.00 | GPR119 (0.52) | GPR119POLBPRMT5WDR77DTYMK | |
| SCHEMBL25471671 | 0.82 | CARM1 (0.53) | GPR119PRMT5WDR77KDM4EPKM | |
| SCHEMBL23922873 | 0.82 | GPR119 (0.47) | GPR119POLB | |
| SCHEMBL23293120 | 0.81 | GPR119 (0.47) | GPR119POLBPRMT5WDR77KDM4E | |
| SCHEMBL2630824 | 0.81 | GPR119 (0.54) | GPR119POLB | |
| SCHEMBL30588466 | 0.81 | EPHX2 (0.50) | GPR119POLBKDM4EPKMKMT2A | |
| SCHEMBL26116336 | 0.81 | EPHX2 (0.50) | GPR119POLBKDM4EPKMKMT2A | |
| SCHEMBL9933273 | 0.80 | POLB (0.53) | GPR119POLBDTYMKKDM4EKMT2A | |
| SCHEMBL28674266 | 0.80 | GPR119 (0.45) | GPR119POLB | |
| SCHEMBL5079976 | 0.79 | GPR119 (0.50) | GPR119PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181136-A | Substituted piperidine compounds and uses thereof | 武田药品工业株式会社 | 2022-03-15 | — | — | CN | disclosed |