Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061544 | 0.84 | GPR119 (0.48) | GPR119 | |
| SCHEMBL3984573 | 0.83 | HMOX1 (0.41) | — | |
| SCHEMBL31496247 | 0.83 | GPR119 (0.48) | GPR119 | |
| SCHEMBL3343608 | 0.82 | GPR119 (0.52) | GPR119PRMT5WDR77 | |
| SCHEMBL3982750 | 0.81 | ALDH1A1 (0.47) | GPR119 | |
| SCHEMBL13690490 | 0.81 | GPR119 (0.48) | GPR119PRMT5WDR77 | |
| SCHEMBL5085887 | 0.81 | GPR119 (0.56) | GPR119 | |
| SCHEMBL940648 | 0.81 | GPR119 (0.66) | GPR119DGAT1 | |
| SCHEMBL30427128 | 0.81 | GPR119 (0.66) | GPR119DGAT1 | |
| SCHEMBL5079865 | 0.81 | GPR119 (0.48) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103123-A1 | New compounds | BIOVITRUM (SE) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103123-A1 | New compounds | GPR119, GPR139, GPR180 | GPR119 1/4885DGAT1 816/4885PRMT5 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.