Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.56 |
| ▸ | FEN1 | P39748 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954348 | 1.00 | ALDH1A1 (0.62) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL11331688 | 0.86 | ERCC5 (0.56) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL31515465 | 0.83 | MAPT (0.49) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL31688020 | 0.83 | CTSL (0.47) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL1855966 | 0.83 | CTSL (0.47) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL4151911 | 0.83 | KCNH2 (0.46) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL2520383 | 0.83 | MAPT (0.49) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL12694520 | 0.81 | MAPT (0.50) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL29403310 | 0.79 | MAPT (0.59) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL11350806 | 0.79 | MAPT (0.59) | ALDH1A1MAPK1HIF1AERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667253-B | Compounds useful for inhibiting RET kinase | 伊莱利利公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-115667253-A | Compounds useful for inhibition of RET kinase | 伊莱利利公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-109280028-B | Quinoline compound and application thereof in DPP-4 enzyme inhibitor | 上海医药工业研究院 | 2022-03-25 | — | — | CN | disclosed |